We are entering an age of superconvergence, in which dizzying advances in artificial intelligence, genetics, biotechnology, automation, advanced materials, energy systems, and other transformative technologies are converging, accelerating one another, and rapidly expanding what humans and our organizations can achieve. At the same time, geopolitical fragmentation, populism, and shifting social expectations are reshaping the world in which these technologies will be developed, governed, and deployed. Read More >

Drawing on the ideas in Superconvergence and his decades of work at the intersection of technology, healthcare, geopolitics, business, and public policy, Jamie Metzl brings these forces together into a single frame in this exciting keynote. Rather than treating AI, biotechnology, global competition, demographic change, and institutional disruption as separate trends, he shows how they interact, reinforce one another, and reshape the strategic landscape in ways that are easy to miss when each is viewed in isolation.

Jamie connects these dots to help leaders see around corners, identify opportunities and risks before they become obvious, and make smarter strategic choices about where to invest, what to build, and how to position their organizations to ride the wave of accelerating change rather than be overwhelmed by it. Read Less ^

For most of human history, medicine has been reactive. We waited for people to get sick and then tried to make them better. As artificial intelligence, genomics, biotechnology, sensors, imaging, and increasingly rich health data come together, that model is now changing. Healthcare is moving toward a world in which we can understand individual risk more precisely, detect disease earlier, design treatments more intelligently, increasingly intervene before illness takes hold, and even alter our underlying biology. Read More >

In this keynote, technology and healthcare futurist Jamie Metzl explores what this extraordinary transformation means for patients, providers, payers, life-science companies, and everyone with a stake in the future of health. Bringing the science vividly to life, he connects the dots across rapidly advancing fields to show not only what is becoming possible, but how these advances are transforming disease detection, drug development, care delivery, and health economics, where the biggest opportunities and risks are emerging, and how today’s choices will shape tomorrow’s outcomes.

By helping audiences see further ahead and understand how these converging technologies will reshape medicine, business models, institutions, and individual lives, Jamie provides a practical framework for navigating this transition intelligently and strategically—and for capitalizing on a new era of medicine focused increasingly on preserving health, extending healthy longevity, and preventing disease before it takes hold. Read Less ^

Artificial intelligence is becoming astonishingly powerful, but much of the debate about its future is still trapped in the misleading idea that intelligence sits on a single ladder, with humans near the top and machines steadily climbing past us. Jamie Metzl offers a very different way of seeing what is coming. Human and machine intelligence are developing along different paths, which means our machines can become vastly better at many consequential tasks without becoming conscious or wise in our way or superior to us at all cognitive tasks. Yet machines do not need to become “generally intelligent” to transform economies, accelerate scientific discovery, reshape work, influence politics, alter the balance of power, and become deeply embedded in our everyday lives. Read More >

In this provocative and fast-moving keynote, Jamie explores how the growing speed, scale, connectivity, and autonomy of AI will expand what individuals, organizations, and societies can do while raising profound new questions about judgment, responsibility, agency, trust, and power.

Drawing on The AI Ten Commandments and his broader work on the future of technology and humanity, Jamie takes audiences beyond the usual hype and fear to focus on the choices that will matter most. Where should we rely on machines, and where must humans remain firmly in charge? Which distinctly human capacities become more valuable as AI improves? How should leaders think about responsibility when decisions are increasingly shared between people and intelligent systems? And how can we use these extraordinary new tools to expand human flourishing rather than merely accelerate the systems and incentives already shaping our world? Read Less ^

Creativity has long felt like one of humanity’s final sanctuaries. Machines might calculate faster and recognize patterns at superhuman scale, but composing a great symphony, writing a profound novel, or creating transformative art seemed to belong to us. Read More >

That assumption is now under direct challenge.

Artificial intelligence can already generate music, images, stories, designs, and scientific insights of astonishing sophistication. As machines become collaborators, competitors, and creators in their own right, we face deeper questions: What is creativity? Does it require consciousness or lived experience? Can something without a body, childhood, mortality, longing, or love create art of lasting human significance?

Jamie Metzl is uniquely positioned to explore these questions. A leading futurist and specialist in emerging technologies, he is also a novelist who has spent years imagining the human consequences of worlds that do not yet exist. Drawing on his novel Virtuosa and developments across AI, neuroscience, robotics, mathematics, music, and the arts, Jamie explores how creative machines may transform culture, originality, genius, and our understanding of what remains uniquely human. The deeper opportunity is to use this extraordinary moment not only to understand what machines can create, but to discover more clearly what human creativity is, why it matters, and how we can cultivate it to enrich our lives and expand what is possible for humanity. Read Less ^

Most people already know the foundations of healthy longevity: exercise, nutrition, sleep, meaningful relationships, and stress reduction. But beneath the hype about “hacking” aging and living forever, something genuinely important is happening. Advances in artificial intelligence, genetics, biotechnology, diagnostics, and preventive medicine are giving us powerful new ways to understand individual risk, intervene earlier, protect our health, and potentially extend both healthspan and lifespan. Read More >

In this eye-opening, optimistic, and highly practical keynote, technology and healthcare futurist Jamie Metzl—who has completed 60 marathons, 40 ultramarathons, and 13 Ironman triathlons—separates credible science from wishful thinking and explores what the emerging science of longevity means for our lives and our society. He shows what individuals can do today to live healthier and more resilient lives, how to position ourselves to benefit from the next generation of predictive and preventive medicine, and how longer, healthier lives could reshape careers, retirement, healthcare, insurance, productivity, public policy, and society itself.

The opportunity is not to chase immortality, but to use the best available science to live better now, prepare intelligently for what is coming next, and ultimately gain more of life’s most precious resource: healthy, meaningful time. Read Less ^